![]() ![]() The majority of opiate addiction starts with prescription drugs. Physical dependence starts after the development, or sometimes in concert with the development of tolerance. However, cross-tolerance does not develop among opiates acting on different receptors. Tolerance depends on the interval between the dosages and the size of the dose.Ĭross-tolerance refers to when a person is tolerant to one opiate, they will also be tolerant of another similar opiate. Tolerance is the need for increased amounts of medication to give the person the same pain relief effects. After 2 to 3 weeks, the physical manifestation starts to be present. It is proposed that tolerance to opiates begins with the first dose. Other side effects are constipation and sometimes bowel obstruction. Often times, when a person presents to the emergency room with a violent cough, they have prescribed codeine. Codeine is an excellent cough suppressant because it is an opiate that suppresses a cough. ![]() This becomes a problem if the person is eating or drinking. In fact, the majority of deaths from opiates are due to respiratory depression. The reason why the respiratory pattern becomes compromised, it is because the opiates interfere with the carbon dioxide that the lungs produce. The reason why the respiratory pattern become slow and shallow. The respiratory pattern becomes slow and shallow. Respiratory depression results from the opiates interfering with the brain respiratory center. With continued use, however, the user has pleasurable experiences, and then they begin to seek out the experience. Interesting enough, the majority of people who are addicted to opiates describe their first encounter with the drug as unpleasant. Long-term opiate users often describe a state of being in euphoria. With repeated use, physical dependence and tolerance will develop. These effects are respiratory depression, sedation, euphoria, and analgesia. What Body Systems Do Opiates Affect?Īlthough opiates affect all body organs and systems, the central nervous system is the most affected. When the opiate receptors are activated, they depressed the symptoms of opiate withdrawal. Opiates work by binding to several opioid receptors in the body. Another word that is interchangeably used for opiates is “opioids”. Originally, opiates were used to describe drugs that were derived from opium.
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